Megaloblastic Anemia

Megaloblastic anemia, with macroovalocytes (thin arrows) and hypersegmented neutrophils (thick arrow).

Mnemonic for ANEMIA: MACROCYTIC = "BIG FAT RED CELLS"

B-B12 Malabsorbtion
I-Inherited
G-Gastrointestinal disease or surgery
F-Folic Acid Deficiency
A-Alcoholism
T-Thiamin responsive
R-Reticulocytes miscounted as large RBCs
E- Endocrine - hypothyroid
D-Dietary
C-Chemotherapeutic Drugs
E-Erythro Leukemia
L- Liver Disease
L- Lesch-Nyhan Syndrome
S-Splenectomy